Granted
The person chooses what may move, to whom and for what purpose. Consent is specific, not a blanket agreement.
Clinical Research
The right study begins with the right context.
Twinome does not run trials. We are building a permissioned context layer that sponsors, CROs and trial sites can use—from participant discovery through longitudinal evidence.
See how matching worksMedications
Clinical
Genome
Physiology
Outcomes
Interventions
Pharmacy
Medication intelligenceLearns with permission
Outcome returned
Consent active
Built around informed participation
Better context before the first visit. Better continuity after it.
Eligibility is written in clinical language, then applied to records that were never assembled for the purpose. The intent is to make each criterion an explainable signal—so a first conversation is specific, honest about what is unknown, and respectful of the person's time.
From criterion to conversation
How an eligibility criterion becomes an explainable match.
Walk one criterion through the intended flow. Illustrative example; no participant data is used.
The protocol states a requirement.
“Adults on stable therapy, no interacting concomitant medication, no contraindicated metabolizer status.” Written for clinicians, not for data.
- 01Criterion
- 02Signal
- 03Context
- 04Reason
- 05Outcome
Three roles. One journey.
Sponsors, CROs and sites each begin from their own priorities.
Design recruitment around the context the protocol actually needs.
Eligibility is written in clinical language and then applied to fragmented data. The intent is to make each criterion an explainable signal, so a study can see who may genuinely fit and why.
What it is designed to give you
- Criteria expressed as transparent, checkable signals
- Discovery that considers medication context, not diagnosis alone
- A consented path from intervention to longitudinal outcomes
What we would ask of you
- A protocol or synopsis with eligibility criteria
- Therapeutic areas and study phases
- The recruitment or evidence problem you want solved
Consent and provenance
Research participation should be a choice a person can see and take back.
No research pathway exists without an explicit permission from the person, and every signal keeps its origin attached through each step.
Scoped
A permission covers a purpose and a period. A research permission does not become a commercial one.
Attributed
Every material signal keeps its origin, method, date and verification state through each hop.
Revocable
A person can withdraw a permission. Future use stops, and the record of what was shared stays visible to them.
The public evidence
Recruitment friction is well documented—and it is a context problem before it is an outreach problem.
19%
of trials closed without meaningful accrual1
Of 2,579 trials examined, 19% either terminated for failed accrual or completed with fewer than 85% of the expected participants—seriously compromising statistical power.
Carlisle et al., Clinical Trials, 201510,252
Phase III trials analyzed2
A 2025 peer-reviewed analysis examined enrollment and dropout across Phase III studies registered on ClinicalTrials.gov.
British Journal of Clinical Pharmacology, 202513.5%
of U.S. adults use five or more prescriptions3
Complex medication histories matter when protocols define concomitant-medication and safety criteria.
CDC/NCHS FastStats, 2024$5.3T
U.S. health system scale4
National health expenditures in 2024—context for the systems, records and workflows research must navigate.
CMS National Health Expenditure, 2024- 1. Carlisle et al., Clinical Trials (2015). Of 2,579 trials examined, 19% either terminated for failed accrual or completed with fewer than 85% of the expected participants—seriously compromising statistical power.
- 2. British Journal of Clinical Pharmacology (2025). A 2025 peer-reviewed analysis examined enrollment and dropout across Phase III studies registered on ClinicalTrials.gov.
- 3. CDC/NCHS FastStats (2024). Complex medication histories matter when protocols define concomitant-medication and safety criteria.
- 4. CMS National Health Expenditure (2024). National health expenditures in 2024—context for the systems, records and workflows research must navigate.
Build with Twinome
Bring the study, the operating challenge or the evidence question.
Our team reviews every submission and follows up where there is a strong fit. Please do not include participant or patient information.
Clinical research
Help make the path to the right study more intelligent.
Tell us where your organization fits and what you want to build. The Twinome team reviews every submission.